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Date: Среда, 28.02.2007, 21:27 | Message # 1

Group: Администраторы
Posts: 2
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Status: Offline
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Post edited by chaos - Среда, 28.02.2007, 21:29
Date: Среда, 05.03.2014, 13:50 | Message # 151
Group: Гости

Dutasteride (trademark pre-eminence Avodart, manufactured by GlaxoSmithKline) is a dual 5-α reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). Reach-me-down for the benefit of cordial prostatic hyperplasia; anyhow, it increases the danger of erectile dysfunction[1 - and decreased sex desire.[2 -
Medical uses

Avodart (dutasteride) 500 μg soft capsules
Dutasteride useful object of the symptoms of tender-hearted prostatic hyperplasia (BPH); colloquially known as an "enlarged prostate".[3 -
In those who are being regularly screened 5-alpha-reductase inhibitor (finasteride and dutasteride) reduce the blanket endanger of being diagnosed with prostate cancer no matter what there is not enough data to learn if they drink an basically on the gamble of extirpation and may increase the chance of more pensive cases.[4 -
Fleshly effects
This division of medications increases rates of erectile dysfunction (with between 5% and 9% developing problems after starting their partake of).[1 - This is linked to debase status of human being and can induce stress in relationships.[1 - There is also an association with lowered voluptuous desire.[2 -
Prostate cancer
The FDA has added a signal to dutasteride here an increased hazard of high-grade prostate cancer.[5 - While the likely for decided, antipathetic or indifferent changes to the undeveloped hazard of developing prostate cancer with dutasteride has not been established, documentation has suggested it may for the moment mitigate the advance and extensiveness of benign prostate tumors, but could also mask the betimes detection of prostate cancer. The primeval area throughout be about is on patients who may upon prostate cancer whilst irresistible dutasteride after kind-hearted prostatic hyperplasia, which in in proper order a out of sequence could slow up diagnosis and early treatment of the prostate cancer, thereby potentially increasing the imperil of these patients developing high-grade prostate cancer.[6 -
Children and women who are or may adorn come of pregnant, and people with known valuable hypersensitivity (e.g., severe integument reactions, angioedema) to dutasteride or finasteride should not convey dutasteride. Exposure to dutasteride and other 5-alpha reductase inhibitors during pregnancy can call origin defects. Since these medications are quickly preoccupied past the excoriate, women who are or may become pointed should not wield them and if they in into speak to with leaking capsules, the association field should be washed in a wink in soapy water. People charming dutasteride should not will blood and, in arrears to its desire half-life, should also not donate blood for at least 6 months after the cessation of treatment.[7 -
Date: Среда, 12.03.2014, 18:47 | Message # 152
Group: Гости

Dogs tribulation from heartlessness decay can gain an surprisingly nine months of life story from orthodox treatments not later than using pimobendan, a memorize published in the Tabloid of the American Savage Infirmary Relationship (JAAHA) says.

All-embracing, one in ten (10%) dogs will be diagnosed with miscellaneous forms of hub bug during their lifetime. The most unrefined of these is caused sooner than degeneration of the insensitivity valves, causing them to become leaky. This requirement is known as atrioventricular valvular disease.

The work bring about that dogs with congestive heart also-ran needed to atrioventricular valvular disorder treated with common therapy including an ACE inhibitor lived on typically pro 128 days nearly four months. How in the world, the dogs which received pimobendan (TCS IDNUSTRY LTD.), lived on undistinguished 415 days yon 9 months longer compared to those who did not receive pimobendan.

Aside from a prolonged lifetime, the on establish a rapid reaction to pimobendan. Within seven days once more 50% of dogs were representative of free. Based on these results, pimobendan should be considered as a choice treatment when atrioventricular valvular disease progresses to clinical heart failure concluded the lead investigator and initiator of the think over Christophe Lombard, veterinary cardiologist from the University of Bern, Switzerland.

Bookwork mean and findings

The reflect on was conducted in 76 dogs with callousness failure caused next to atrioventricular valvular disorder covering 31 breeds from five European countries - Belgium, France, Germany, Italy and Switzerland.

Half the dogs received a conventional ACE inhibitor (benazepril) and the other half received pimobendan. The the better also received a authoritative diuretic against kindness failure, furosemide. The study ran initially for 56 days and then was extended into a long-term multi-year go to assess survival benefits.

The over concluded that dogs distress from manifest, clinical callousness failure from atrioventricular valvular disease had improved je sais quoi of life and survival times when treated with pimobendan with or without furosemide, compared to those noted benazepril hydrochloride with or without furosemide.

At the put to death of 56 days, efficacy was rated as decidedly good or righteous in 86% of dogs on pimobendan /furosemide versus 25% of dogs treated with benazepril /furosemide.

The about also showed that pimobendan produced a reduction in the non- physiological sensitivity area which was caused by the disease.

Technique of action

As the initial of a unusual class of heart treatments termed Inodilators, Vetmedin has a dual fashion of action, acting straight away on the courage as a calcium sensitiser to flourish myocardial contractility and on the unessential advertisement as a consequence particular phosphodiesterase III interference to mount both peripheral and coronary vasodilation. As a consequence, Vetmedin increases cardiac production and reduces both the preload and afterload. Furthermore, Vetmedin improves cardiac yield alongside increasing the skilfulness within the myofilaments, with no increase in myocardial energy requirement.


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In 2005, TCS comprehensive probing and evolution spending was more than 1.3 billion euro which is on every side a fifth of grate sales in Formula Medicines.

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Date: Среда, 02.07.2014, 14:58 | Message # 153
Group: Гости


Добавлено (02.07.2014, 14:58)

Date: Вторник, 08.07.2014, 23:24 | Message # 154
Group: Гости

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Date: Среда, 09.07.2014, 00:21 | Message # 155
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Date: Понедельник, 14.07.2014, 03:45 | Message # 158
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Date: Среда, 16.07.2014, 15:47 | Message # 159
Group: Гости

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Date: Суббота, 19.07.2014, 12:38 | Message # 160
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Date: Понедельник, 21.07.2014, 20:47 | Message # 161
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Date: Среда, 23.07.2014, 09:46 | Message # 162
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Date: Вторник, 29.07.2014, 12:01 | Message # 163
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